Artificial Gene Network Series Century
This series consists of 150 artificial gene networks. Each network consists of 100 genes with a total of 200 gene interactions (on average each gene has 2 modulators). All networks are composed of genes with similar kinetics, the only difference between networks is how the gene interactions are organized (i.e. which genes induce and repress which other genes). The networks belong to three major groups according to their topologies.
Each artificial gene network is like an in silico organism, which is used to carry out simulations of experiments. Data is available for:
- null mutant experiments, where genes were deleted, one at a time, and steady-state gene expression levels are provided without noise. The tab delimited file includes the wild-type levels on the first row, followed by each of the null mutants (G1, G2, etc.) line by line. The columns represent the level of each gene (G1, G2, etc.).
Models are provided in Gepasi input files and SBML level 1 format; simulation results are supplied in tab delimited ASCII files. Models, data and network details are available in each network's summary page or within a single compressed file.
The complete series is available in one single file: AGN-Century.zip (62 Mb). This file contains all the model and data files, as well as all the HTML pages (including this one).